For whom is this information?
This information is meant primarily for people with the hyper-IgD syndrome (also abbreviated to HIDS). Here you’ll find among other things general information on the disease, the tests that can be done, what is known about treatment and about heredity. You may come to some information which does not directly concerns you, but which applies to others with this disease. It might be useful for your partner, relatives and friends to read this brochure as well. That will make it easier to think about and discuss the disease.
HIDS is a rare disorder, which has only been appreciated for the last few years. Many doctors will therefore hardly know about this syndrome, if at all. At the department of General Internal Medicine of the University Medical Center St. Radboud, Nijmegen, in the Netherlands, there is a research interest in HIDS and other periodic fever syndromes. This research group has also initiated a website with information on HIDS (hids.net).
If you have questions after reading this information, don’t hesitate to get answers. You can contact us or of course your own specialist or family doctor. We would also like to hear any comments on or suggestions for improvement for this brochure.
HIDS in brief
The hyper-IgD syndrome, which can yet be abbreviated to HIDS, is a rare disorder involving repeated episodes of high fever accompanied by other signs of inflammation, like swollen lymph nodes, fatigue, headache, muscle ache and stomach ache. Such a fever attack usually lasts a few days, after which it disappears spontaneously. In blood samples, high levels of a certain protein, the IgD, are found. It is a hereditary disease, and DNA-tests can be performed to diagnose the syndrome.